摘要
目的:建立黄连及其炮制品、川白芷中5种重金属的最大限量标准。方法:采用微波消解法消解样品后,用原子荧光分光光度法测定药材中汞(Hg)、砷(As)的含量,用原子吸收分光光度法测定药材中铅(Pb)、镉(Cd)、铜(Cu)的含量。结果:黄连中除As以外,其余重金属含量均超标;川白芷中除Cu超标外,其余重金属含量均未超标。结论:建议将黄连、川白芷中重金属含量限度规定为:Pb≤5.0μg·g-1、Hg≤0.2μg·g-1、As≤2.0μg·g-1、Cu≤20.0μg·g-1、Cd≤0.3μg·g-1。
OBJECTIVE： To establish the maximum limits of 5 heavy metals in Coptidis Rhizoma and processed product and Angelica dahurica. METHODS： Samples were digested with microwave digestion system, and the contents of As and Hg were analyzed by atomic fluorescence spectrometric, and the contents of Pb, Cd and Cu were analyzed by atomic absorption spectrophotometry. RESULTS： Except As, all the other heavy metals in Coptidis Rhizoma exceed the criteria; As for ,4. dahurica, all the heavy metals are within the standard except Cu. CONCLUSION： The maximum limits of Pb, Hg, As, Cu , Cd in samples were 5.0 μg·g^-1,0.2 μg·g^-1,2.0 μg·g^-1,20.0μg·g^-1, 0.3 μg·g^-1, respectively.
出处
《中国药房》
CAS
CSCD
2012年第11期999-1001,共3页
China Pharmacy
基金
国家科技支撑计划课题(2007BAI40B03)
关键词
黄连
川白芷
重金属
限量
Coptidis Rhizoma
Angelica dahurica
Heavy metals
Limit
