摘要
目的对我院肿瘤内科不良反应(ADR)的发生情况及特点进行分析,为临床合理用药提供参考。方法采用回顾性分类统计,对164例报告涉及的患者年龄、性别、给药途径药物类别以及临床表现进行分析。结果 164例ADR中男性76例,女性88例;40岁以上154例;细胞毒类药物的发生率居首,占77.9%;ADR的临床表现以消化系统反应为主,其次为骨髓抑制。结论开展ADR监测工作是医务人员,特别是临床药师的重要任务,加强ADR监测,保障患者用药安全。
Objective To provide reference for clinical rational drug use,the tumor patients＇s adverse drug reacton（ADR） occurrence and characteristics in our hospital were analyzed.Methods In this paper,164 cases of patients with anti-tumor drug adverse reaction reports were retrospective analyzed on the age,sex,administration way,drug classes and clinical manifestations.Results The results showed that adverse drug reacton mainly happened in the 40 years and old tumor patients.Cytotoxic drugs take the highest incidence.The clinical manifestations of adverse drug reacton in gastrointestinal reaction is given priority,followed by bone marrow inhibition.Conclusion Adverse drug reacton monitoring and reporting work which ensure patients safely use their drugs is the medical staff,especially the clinical pharmacists important task.
出处
《中国药物警戒》
2012年第3期184-186,共3页
Chinese Journal of Pharmacovigilance
关键词
抗肿瘤药物
不良反应
合理用药
antitumor drugs
adverse drug reacton
rational drug use
