摘要
目的比较罗哌卡因与罗哌卡因＋可乐定硬膜外麻醉应用于剖官产手术的麻醉效果。方法选择102位在硬膜外麻醉下行剖宫产手术的足月单胎初产妇，随机、双盲分成两组：罗哌卡因组（R组）用药为0．75％罗哌卡因12ml，罗哌卡因＋可乐定组（RE组）用药为0．75％罗哌卡因12ml＋可乐定75斗g，麻醉平面最高达到T6～T7，术中观察记录两组产妇的麻醉效果、心率、血压及新生）mApgar评分及围术期不良反应。结果两组产妇的人口学特征、新生）kApgar评分及不良反应差异无显著性。RC组的镇痛起效时间为8．64min，完全起效时间为12．26min，运动阻滞时间为17．34rain，均短于R组的11．36min、15．12rain、21．70min，差异有显著性（P〈0．05）。RC组牵拉痛率为20．4％、寒战发生率为7．4％，均低于R组的66．7％、33．3％，差异有显著性（P〈0．05）。结论可乐定＋罗哌卡因合用于硬膜外麻醉下剖宫产，可缩短罗哌卡因的麻醉起效时间、减小寒战等副作用。
Objective To evaluate the effects of clonidine added to ropivacaine for epidural anesthesia of cesarean section. Methods 102 pregnant women for elective cesarean section under epidural anesthesia were selected and randomly divided into two groups：（R group） received 0.75% ropivacaine 12 ml,（RC group） received 0.75% ropivaeaine 12 ml added clonkhne 75μg, two groups of epidural anesthesia were performed at T6-T7.The effects of anesthesia, the maternal heart rate and blood pressure, the neonatal Apgar score and perioperative adverse reactions were recorded.Results Two groups of demographic characteristics, neonatal Apgar score and adverse reaction had no significant difference, the analgesic effect to time, fully work time and the onset time of motor block were significantly shorter than those in group RC as compared with group R（P〈 0.05）. Conclusion The addition of elonidine to ropivacaine under epidural anesthesia for cesarean section can shorter the effect time of anesthesia and reduced the shivering side effect.
出处
《国际医药卫生导报》
2012年第4期479-481,共3页
International Medicine and Health Guidance News
关键词
可乐定
剖宫产
硬膜外麻醉
罗哌卡因
Clonidine
Cesarean section
Epidural anesthesia
Ropivacaine
