期刊文献+

火灾烟气毒性蛋白质组学研究进展

The Research Progress of Toxicoproteomics of Combustion
下载PDF
导出
摘要 毒理蛋白质组学(toxic proteomics)整合了经典毒理学、病理学和蛋白质差异表达技术,形成潜在的强有力的毒性风险评价工具。本文介绍了火灾烟气毒性研究的现状,并指出在火灾烟气毒性研究中使用蛋白质组学的研究手段必将使火灾烟气毒性致毒机理、生物标志物和代谢产物等方面的研究取得重大进展。 Toxicoproteomics that integrates classic toxicology,pathology and protein express analysis technology has promoted toxicology to a new level.Toxicoproteomics is defined as a study that is important in responses to fire gas toxicant exposures.This article presented the progress of combustion toxicology.And it pointed out that the research of combustion toxicology will make a great progress by the application of toxicproteomics.
出处 《中国西部科技》 2012年第3期33-34,共2页 Science and Technology of West China
基金 "十二五"计划"材料及制品的防火阻燃性能及火灾危险性评价新技术研究"资助
关键词 毒理蛋白质组学 火灾烟气毒性 Toxicoproteomics Combustion toxicology
  • 相关文献

参考文献12

  • 1Ferguson,G.E.[J].Fire Gases.,Q.Natl.Fire Protect.Assoc.1933,27,10.
  • 2Zapp,J.A.[J].The Toxicology of Fire,Medical Division Special Report1951,No.4,Chemical Corps Army Chemical Center,MD.
  • 3Cann.R G,Aveirll J D,Butler K M et al.International study of the sub一lethal effects of fire smoke(SEFS)on survivability and health.Phase lfinal report.N IST Technical Note14 39[R].National Institute ofStandard and Technology,Gaithersburg,MD(2001,8).
  • 4Smith,R.P.[J].Toxic responses of the blood.In:C.D.Klaassen,M.O.Amdurand K.Doull(Eds),Casarett and Doull’s Toxicology:The Basic Science ofPoisons,Third Edition,Chapter 8.1986,Macmillan PublishingCompany,New York:228-231.
  • 5Hartzell,G.E.,Switzer,W.G.and Priest,D.N.[J].Modeling of toxicologicaleffects of fire gases:V.mathematical modeling of intoxication of rats bycombined carbon monoxide and hydrogen cyanide atmospheres;J.FireSci.1985,3:330-342.
  • 6Harold L K,ArthurF G,G ordon HartsellE;Combustion ToxicologyPrinciples and Test M ethods.[M].TECHNOMIC PublishingCo.In,1983.
  • 7PottsW.J,LedererT.S;A method for comparative testing of smoke toxicity.[J].Journal of Combustion Toxicology.1977,4:114-162.
  • 8RobinsonR S,Dressler D P,Dugger D L,et al;Smoke toxicity of fire-retardant television cabinets.[J].Journal of Combustion Toxicology,1977,4:4-35.
  • 9Lee,H.M.,Greeley,G.H.,Herndon,D.N.,Sinha,M.,Luxon,B.A.,Englander,E.W.,2005.A rat model of smoke inhalation injury:influence ofcombustion smoke on gene expression in thebrain.Toxicol.Appl.Pharmacol.208,255-265.
  • 10Chen,L.,Lee,H.M.,Greeley Jr.,G.H.,Englander,E.W.,2007.Accumulationof oxidatively generated DNA damage in the brain:a mechanism ofneurotoxicity.Free Radic.Biol.Med.42,385-393.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部