1Meng X,Mojaverian P,Doedee M,et al.Bioavailability of amiodarone tablets administered with and without food in healthy subjects[J].Am J Cardiol,2001,87(4):432-435.
2Petr P,Verner M,Van Wyk CJ,et al.Amiodarone-excellent antiarrhythmic drug?(Happy end after 40 years of problems)[J].J Appl Biomed,2003,1(3):127-139.
3Ohyama K,Nakajima M,Nakamura S,et al.A significant role of human cytocchrome P4502C8 in amiodarone N-deethylation:An approach to predict the contribution with relativeactivity factor[J].Drug Metab Dispos,200,28(10):1303-1310.
4Roden DM.Mechanism underlying variability in response to drug therapy:Implications for amiodaron use[J].Am J Cardiol,1999,84 (Supp l.1):s29-s36.
1McGarry SJ, Williams AJ. Digoxin activates sarcoplasmic reticulum Ca2+ release channels: A possible role in cardiac inotropy. Br J Pharmacol,1993,108:1043.
2Vorperian VR, Havighurst TC, Miller S, et al. Adverse effects of low dose amiodarone; A meta-analysis. J Am Coll Cardiol, 1997,30:791.
3Verduyn SC, Vos MA, Zande JVD, et al. Further observation to elucidate the role of interventricular dispersion of repolarization and early afterdepolarization in the genesis of acquired torsade de points arrhyth mias. J Am Coll Cardiol,1997,30:1575.
4Nishimura M, Follmer CH, Cigan AL,et al. Amiodarone blocks Ca2+ current in guinea pig myocytes. Circulation, 1986,74: Ⅱ.
5Follmer CH, Aomine M, Yeh JZ, et al. Amiodarone-induced block of sodium current in isolated cardiac cells. J Pharamacol Exp Ther, 1987,243:187.
6Sicouris S, Antzelevitch C. A subpopulation of cells with uniqne electrophysiological properties in the deep subepicardium of the canine ventricle:the M cell. Circ Res, 1991,68:1729.
7Antzelevitch C, Sicouris S. Drug-induced afterdepolarizations and triggered activity occur in a discrete subpopulation of ventricular muscle cells ( M cells ) in the canine heart: Quinidine and Digitalis. J Cardiovasc Electrophysiol, 1993,4:48.
8Dronin E, Charpentier F, Gauthier C, et al. Electrophysiological characteristics of cells spanning the left ventricular wall of human heart:evidence for presence of M cells. J Am Coll Cardiol, 1995,26:185.
9Podrid PJ. Amiodarone: Reevaluation of an old drug. Ann intern Med,1995,122:689.
10Bajaj BP, Baij MW, Perrins EJ. Amiodarone-induced torsades de points: the possible facilitatory role of digoxin.Int J Cardiol, 1991,33:335.
9Walker Nil, Curtis MJ, Hearse DJ, et al. The Lambeth Conven- tions: guidelines for the study of arrhytbmias in ischemia infarction and reperfusion. Cardiovasc Res, 1988,22(7) :447-455.
10Varbior G, Toth A, Tapodi A, et al. Protective effect of amio- darone but not N-desthlamiodarone on postischemic heart through the inhibition of mitochondrial permeability transition. J pharmacol Exp Ther, 2003,9 (2) : 616-625.
