摘要
目的综述抗高血压药物联合用药研究进展,为临床合理用药提供参考。方法检索国内外相关文献,对有关抗高血压联合用药的文献进行整理综述。结果临床常用的6类抗高血压药物中,钙离子拮抗剂(CCB)、利尿剂联合用药最广泛,其中CCB联用血管紧张素转化酶抑制剂(ACEI)或血管紧张素受体拮抗剂(ARB)是临床最佳的联用方案。结论大量的循证医学和临床研究显示,抗高血压药物联合用药是有效控制血压、降低不良反应的有效途径。
Objective Summarize research progress on anti-hypertensive drug combination therapy,and provide reference for clinical use of drugs.Methods Retrieve the relevant literature,and review anti-hypertensive combination therapies.Results In six kinds of commonly used anti-hypertensive drugs,calcium channel blocker（CCB） and diuretics are the most extensive combination therapy,in which CCB combined with angiotensin-converting enzyme inhibitors（ACEI） or angiotensin receptor blocker（ARB） is the best clinical programs in conjunction with anti-hypertensive.Conclusion Large number of evidence-based medicine and clinical studies have shown that anti-hypertensive drug combination therapy is an effective way to control blood pressure and reduce adverse reactions.
出处
《中国药事》
CAS
2012年第1期80-83,共4页
Chinese Pharmaceutical Affairs
关键词
抗高血压药物
联合用药
研究进展
anti-hypertensive drugs
combination therapy
research progress
