摘要
目的观察米非司酮配伍米索前列醇用于高危妊娠引产的效果。方法将60例高危妊娠患者随机分为观察组和对照组各30例。观察组给予米非司酮配伍米索前列醇引产,对照组给予依沙吖啶羊膜腔内注射引产。观察2组引产结局和并发症发生情况。比较2组用药至宫缩时间、宫缩至胎儿胎盘娩出时间、用药至胎儿胎盘娩出时间。结果观察组引产成功率高于对照组,并发症发生率低于对照组,观察组用药至宫缩时间、宫缩至胎儿胎盘娩出时间、用药至胎儿胎盘娩出时间均短于对照组,差异均有统计学意义(P<0.05)。结论米非司酮配伍米索前列醇用于高危妊娠引产安全有效。
Objective To observe the effect of mifepristone combined with misoprostol in labor induction of high-risk pregnancy.Methods 60 cases patients with high-risk pregnancy were randomly divided into observation group and control group,each of 30 cases.Observation group were given mifepristone combined with misoprostol,while control group were given ethacridine intra-amniotic injection.Observed abortion outcome and complication of two groups.Compared the time of treatment to contraction,placenta to the fetus and treatment to fetal placenta of two groups.Results Induction success rate of observation group was higher than that of control group,the complication rate was lower than that of control group,the time of treatment to contraction,placenta to the fetus and treatment to fetal placenta of observation group were shorter than those of control group,the difference were statistically significant(P0.05) .Conclusion Mifepristone combined with misoprostol in labor induction of high-risk pregnancy is safety and effective.
出处
《临床合理用药杂志》
2012年第7期38-39,共2页
Chinese Journal of Clinical Rational Drug Use