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梅毒检测研究进展 被引量:29

Advances in Syphilis Detection
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摘要 梅毒是由梅毒螺旋体引起的一种慢性细菌感染性疾病,目前仍是世界范围内的公共卫生问题。控制梅毒的主要措施是早期发现梅毒感染并给予及时治疗。目前梅毒的诊断主要依靠实验室检测,特别是血清学抗体和暗视野检测。近年来出现的以重组梅毒螺旋体抗原为基础的聚合酶链式反应、梅毒快速诊断试验及梅毒螺旋体免疫球蛋白M抗体检测,对不同病期的梅毒患者都具有一定的敏感性和特异性。 Syphilis, a chronic bacterial infection caused by the spirochete Treponema paUidum subsp pallidum cation an , remains a public health concern worldwide. Syphilis control is largely dependent upon early identifid prompt treatment. The diagnosis of syphilis is mainly based on laboratory tests, especially serology and darkfield microscopy. In recent years, recombinant Treponema pallidum antigenbased rapid tests, polymerase chain reaction, and immunoglobulin M antibody detection have also shown certain sensitivities and specificities for syphilitic patients at different stages.
作者 李军 郑和义
出处 《中国医学科学院学报》 CAS CSCD 北大核心 2012年第1期95-98,共4页 Acta Academiae Medicinae Sinicae
关键词 梅毒 检测 聚合酶链式反应 免疫球蛋白M抗体 梅毒快速诊断试验 syphilis tests polymerase chain reaction immunoglobulin M antibody rapid tests for syphilis
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