摘要
目的了解我国不同民族的健康人群戊型肝炎病毒感染情况。方法采用ELISA方法检测人群血清中戊型肝炎病毒（戊肝，HEV）IgG抗体。汉族人群血清分别来自于四川、北京、黑龙江和山东，回族和藏族人群血清来自于甘肃、宁夏和青海，总共10448份血清采集于2006—2008年。结果七省市人群HEV抗体总阳性率为17．97％（1878／10448）。汉、回和藏不同民族人群HEV抗体阳性率分别为24．32％（1794／7376）、3．59％（81／2258）和0．37％（3／814）。不同地区人群HEV抗体阳性率分布，四川、北京、黑龙江和山东汉族人群阳性率分别为27．45％、20．30％、22．89％和22．68％，甘肃汉和回族分别为24．63％（184／747）和6．12％（77／1258），宁夏回族和青海藏族分别0．40％和0．37％。汉回藏不同民族各年龄组人群HEV感染分布，汉族各年龄组人群HEV抗体阳性率，在≤10岁年龄组为5．19％，11～20岁组为11．64％，21～30岁组为20．08％，31～40岁组为34．17％，41—50岁为41．75％，51～60岁组为48．58％，≥61岁组为57．43％。回族人群各年龄组人群HEV抗体阳性率依次为3．11％，3．96％，2．11％，3．98％，2．52％，4．57％和6．67％。藏族人群3份阳性者分布在21—30岁组、31—40岁组和51～60岁组各1份，阳性率为0．63％、0．58％和1．01％。结论汉族人群戊肝病毒感染明显高于回族和藏族，感染率随年龄增长而升高。回藏族人群HEV抗体阳性率低下，应加强对HEV感染的监测。
Objective To investigate the seroprevalence of HEV infection in different national human population in Han, Hui and Zang in China . Methods EIA was used for detecting anti-HEV IgG of the serum samples. All samples were collected in 2006-2008 in Siehuan, Beijing, Heilongjianin, Sandong, Gansuo, Ningxia and Qinghai areas. Results The total positive rate of anti-HEV IgG was 17.97% （ 1878/ 10448） ,24. 32% （1794/7376）in Han national, 3.59% （81/2258） of Hui national and 0. 37% （3/814） of Zang national,respectivelyo The positive rate of Han human at different age group, was 5.19% of ≤ 10 year, 11.64% ofll-20 year, 20.08% of 21 -30 year, 34. 17% of 31 -40 year, 41.75% of 41 -50 year, 48.58% of 51 -60 year,57.43% of ≥ 61 year. The positive rate of Hui human at different age group, was 3.11% , 3.96% , 2.11% , 3.98, 2. 52% , 4.57% and 6.67% , respectively. Three positive of Zang human was between 21 -60 year. Conclusions The HEV infection in Han national population was higher than the Hui and Zang national, significantly. The HEV infection was correlation with age significantly, the infection rate was increased with age.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
2012年第1期46-47,共2页
Chinese Journal of Experimental and Clinical Virology
关键词
肝炎病毒
戊型
感染
血清学
Hepatitis E virus
Infection
Serology
