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冠心病患者颈动脉粥样硬化的性别差异 被引量:12

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摘要 目的研究冠心病患者颈动脉粥样硬化的性别差异,为冠心病患者诊断和防治的性别差异提供依据。方法 209例经冠状动脉造影证实的冠心病患者按性别分为女性冠心病组和男性冠心病组。利用高频超声检测患者颈动脉内膜中层厚度与粥样斑块。登记患者年龄、体质指数(BMI)、血糖、血脂、血压与高敏C反应蛋白(hs-CRP)。结果女性冠心病组颈动脉内膜中层厚度小于男性冠心病组,女性冠心病组颈动脉斑块发生率也低于男性冠心病组,差异均有统计学意义(P<0.05)。女性冠心病组年龄、收缩压、脉压、TC和HDL-C大于男性冠心病组,差异有统计学意义(P<0.05)。女性冠心病组LDL-C小于男性冠心病组,差异有统计学意义。女性冠心病组和男性冠心病组间TG、FPG、2hPG、糖化血红蛋白、hs-CRP、BMI和舒张压差异均无统计学意义(P>0.05)。结论冠心病患者颈动脉粥样硬化存在性别差异,临床应用颈动脉超声检查指导冠心病诊治时必须考虑性别因素。冠心病患者颈动脉粥样硬化的危险因素也存在性别差异,提示冠心病的防治也需考虑性别的差异性。
出处 《广东医学》 CAS CSCD 北大核心 2012年第4期492-494,共3页 Guangdong Medical Journal
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参考文献9

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