摘要
目的比较胰腺癌姑息手术中楔形活检与一次性自动活检枪活检的差别。方法对华中科技大学协和医院胰腺外科中心2006年3月25日至2011年3月25日217例胰腺癌姑息手术术中行活检患者的临床资料进行回顾性分析。根据活检方式不同分为楔形活检组（A组，120例）和一次性自动活检枪活检组（B组，97例）。比较两组的活检成功率、活检阳性率、诊断准确率及术后并发症发生率。结果A组与B组的活检成功率、活检阳性率、诊断准确率、术后出血发生率分别为：100％、97．5％、97．5％、1．7％与100％、99．0％、99．0％、1．0％，差异无统计学意义（P〉0．05）。A组与B组术后胰漏发生率分别为11．7％、2．1％，差异有统计学意义（P=0．007）。结论在不可切除胰腺癌姑息手术的活检中，与楔形活检相比，一次性自动活检枪活检在未影响活检成功率、活检阳性率和诊断准确率的前提下，显著降低术后胰漏发生率且术后出血发生率并未增加，是一种安全，可靠的活检方式。
Objective To compare wedge biopsy and disposable automatic biopsy gun biopsy for the diagnosis of pancreatic cancer. Methods The clinical data of 217 patients with unresectable pancreatic cancer undergoing palliative operation and biopsy were retrospectively analyzed in our hospital from March 25,2006 to March 25,2011. Group A（wedge biopsy） consisted of 120 cases and B（ disposable automated biopsy gun biopsy） of 97 cases. The success rate of biopsy, the positive rate of biopsy, the accuracy of diagnosis and the incidence of postoperative complications were calculated. Results The success rate, positive rate, diagnostic accuracy and the incidence of postoperative hemorrhage of group A and B were 100%, 97. 5%, 97. 5% , 1.7% and 100% , 99%, 99%, 1.0%, respectively （ all P 〉 0. 05 ）. The incidence of postoperative pancreatic leakage in group A and B were 11.7% and 2. 1% （P = 0. 007）. Conclusions Intra-operative biopsy for the diagnosis of pancreatic cancer using disposable automated biopsy gun biopsy has significantly decreased the incidence of post-biopsy pancreatic leakage as compared with wedge biopsy.
出处
《中华普通外科杂志》
CSCD
北大核心
2012年第2期151-154,共4页
Chinese Journal of General Surgery
关键词
胰腺肿瘤
活组织检查
手术后并发症
Pancreatic neoplasms
Biopsy
Postoperative complications
