摘要
目的探讨黛力新联合心理干预治疗对偏头痛患者的疗效。方法随机将60例偏头痛患者分为两组,对照组常规治疗,治疗组联用黛力新和心理治疗,疗程8周。两组在入组前及治疗后8周分别记录临床症状,观察药物的不良反应,并同步进行90项症状自评量表(SCL-90)总分评定和5-羟色胺含量的测定,随访1年。结果治疗组有效率90.0%,对照组有效率73.3%,两组比较差异具有统计学意义(χ2=4.565,P<0.05);1年后随访,治疗组30例无一例复发,而对照组6例复发,差异具有统计学意义(χ2=5.163,P<0.05)。治疗8周后两组SCL-90总分和血5-羟色胺的下降幅度治疗组明显高于对照组。结论联用抗焦虑药物和心理综合方法治疗偏头痛患者,临床症状改善明显,不良反应小,复发率低。
Objective To investigate the curative effect of deanxit combined with psychological intervention for the treatment of migraine patients.Methods 60 migraine patients were divided into two groups,control group with conventional treatment for migraine while the case group combined with deanxit and psychological treatment,all treatment continued for 8 weeks,of the two groups,before and after treatment 8 weeks.Both groups were recorded clinic symptoms and were assessed by symptom checklist-90（SCL-90）score,plasma 5-HT was also detected at the same time.All of patients were followed-up for 1 year.Results In treatment group,the effective rate was 90.0% while 73.3% in the control group,the difference was statistically significant（χ2=4.565,P〈0.05）;with 1-year follow-up,in the treatment group,all 30 cases had no recurrence,while the control group 6 cases of recurrence,the difference was statistically significant（χ2=5.163,P〈0.05）.After 8 weeks of the treatment,the decline of SCL-90 total score and blood 5-HT in treatment group were significantly higher than that in control group.Conclusion Clinical symptoms improved significantly when comprehensive anti-anxiety drugs combined with psychological treatment for patients with migraine,are administered the recurrence rate and side effects are lower.
出处
《医学综述》
2012年第4期630-631,共2页
Medical Recapitulate
关键词
偏头痛
黛力新
心理干预
Migraine
Deanxit
Psychological intervention
