摘要
目的研究煤工尘肺患者慢性阻塞性肺疾病（COPD）的合并率，以及煤工尘肺期别、接尘工龄、年龄、吸烟对合并慢性阻塞性肺疾病（COPD）的影响；相对于慢性支气管炎所致COPD的患者，分析煤工尘肺合并COPD患者治疗前后肺功能的变化。方法回顾性分析2010年8月至2011年7月在黄石市第二医院住院的220例煤工尘肺患者COPD的合并率。选择煤工尘肺合并COPD患者28例为观察组，慢性支气管炎所致COPD的患者30例为对照组，两组都给予氧疗、抗感染、祛痰、平喘等处理，对比分析两组患者治疗前后的血气分析和肺功能。结果煤工尘肺患者COPD合并率为69．09％，煤工尘肺随着期别的增加，合并COPD率增高。随着接尘工龄、年龄的增加，煤工尘肺合并COPD率有增高的趋势，吸烟的煤工尘肺患者合并COPD率较不吸烟者有增高。对照组的用力肺活量占预期值百分比（FVC％）、第1秒用力呼气容积／用力肺活量（FEVl／FVC）、第1秒用力呼气容积／预期值百分比（FEVI％）增加幅度较观察组明显，对照组动脉血氧分压比观察组提高更明显，而二氧化碳分压下降也更显著，差异有统计学意义（P〈0．05）。结论煤工尘肺的期别、接尘工龄、年龄、吸烟影响到COPD合并率，煤工尘肺合并COPD患者经积极治疗，血气分析和肺功能改善情况无慢性支气管炎所致COPD患者明显。
Objective To investigate the incidence of chronic obstructive pulmonary disease （COPD） in coal worker＇s pneumoeoniosis（CWP） patients, and the effect of the CWP level, histories of coal dust-exposure, smoking and age on COPD in CWP. Compared with COPD in chronic bronchitis fac- tor, to analyze the change of lung function and blood gas analysis of COPD in CWP before and after treat- ment. Methods The incidence of COPD among 220 inpatients with CWP in our hospital from August 2010 to July 2011 was retrospectively analyzed. Patients in the observed group （28 cases with COPD in CWP） and control group （30 cases with COPD in else factors） were both given oxygen treatment, anti- infection, dispel phlegm and antispasm treatment. The data of lung function and blood gas were analysed before and after treatment. Results The incidence of COPD in CWP was 69.09% , which increased with the increase of CWP level, and there was significant difference between the smoking group and the non-smoking group （ P 〈 0.05）. The incidence of COPD in CWP increased with age and exposure time. The increasing rate of FVC % , FEV1/FVC（ % ）, FEV1% of the control group was more than that of the observed group （ P 〈 O. 05）. Conclusions The CWP level, histories of coal dust-exposure, smoking and age are influencing factors of the incidence rate of COPD in CWP. On the basis of effective treatment, the pulmonary ventilation and blood gas analysis improvement of COPD in CWP are not more than that of COPD caused by chronic bronchitis.
出处
《中国实用医刊》
2012年第6期20-22,共3页
Chinese Journal of Practical Medicine
关键词
煤工尘肺
慢性阻塞性肺疾病
肺功能
血气分析
Coal worker＇s pneumoconiosis
Chronic obstructive pulmonary disease
Fulmonaryfunction
Blood gas analysis
