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青壮年冠心病的危险因素及冠状动脉病变特点 被引量:4

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摘要 目的探讨青壮年冠心病(CHD)的危险因素及其冠状动脉病变特点。方法随机选择2010年7月至2011年7月住院的110例青壮年冠心病患者(〈45岁)为实验组(A组)、60例青壮年非冠心病患者(〈45岁,B组)及71例老年冠心病患者(〉60岁,C组)为对照组,比较三组间冠心病危险因素的差异,分析青壮年冠心病组不同诊断间危险因素的相关性,并通过冠状动脉造影结果分析青壮年冠心病冠状动脉病变的特点。结果A组中性别、冠心病家族史、高血压病及2型糖尿病的比例远高于B组,体质量指数(BMI)、吸烟指数、血清铜蓝蛋白(Cp)、总胆固醇(Tc)、甘油三酯(TG)及C-反应蛋白(CRP)的水平均高于B组,差异有统计学意义(P〈0.05);与C组相比,A组性别、冠心病家族史、TG及CRP的水平明显偏高,而2型糖尿病、高血压病、吸烟指数、BMI、Cp及TC的水平比较差异无统计学意义(P〉0.05);随病情严重性增加,A组吸烟指数、BMI、Cp及CRP的水平逐渐升高(P〈0.05);青壮年冠心病患者冠状动脉多以单支病变为主,且多为左前降支病变,而双支及多支病变比例则低于老年冠心痛患者(P〈0.05)。结论吸烟、高血压病、糖尿病、冠心病家族史、肥胖及血脂代谢异常是青壮年冠心病的危险因素,改善生活方式及饮食习惯、戒烟、加强体育锻炼有助于预防和减少青壮年冠心病的发生。
出处 《中国实用医刊》 2012年第6期62-64,共3页 Chinese Journal of Practical Medicine
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参考文献9

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