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猪链球菌河北分离株对常用抗菌药物的耐药性 被引量：2

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摘要 采用微量稀释法测定了28种药物对临床分离的34株猪链球菌的体外最小抑菌浓度(MIC),以美国临床检验标准委员会(NCCLS)的临界浓度做为判断标准,判定了猪链球菌对28种药物的耐药谱。结果表明,临床分离的菌株以耐药菌为主,且91.18%的菌株呈多重耐药,菌株耐药谱型达14种,对磺胺类药物(82.3%～100.0%)、氨基糖苷类药物(79.4%～94.1%)、四环素类药物(88.2%～97.1%)、林可胺类药物(79.4%～85.3%)、大环内酯类药物(50%～88.2%)耐药性最为严重,对β-内酰胺类(14.7%～35.3%)、喹诺酮类(38.2%～73.5%)、酰胺醇类(32.4%～41.2%)耐药性次之,对头孢菌素类药物头孢噻呋和头孢唑啉、头孢噻吩敏感率分别为85.3%和82.3%。
作者 芮萍 陈翠珍 段玲欣 王秋悦 杨彩然 马增军
机构地区 河北科技师范学院河北省预防兽医学重点实验室
出处 《中国兽医杂志》 CAS 北大核心 2012年第2期75-77,共3页 Chinese Journal of Veterinary Medicine
基金 河北省自然科学基金资助项目(C2009000877) 河北省科技厅科技支撑项目(09220402D) 河北省教育厅计划项目(2008448)
关键词 猪链球菌 微量稀释法 体外最小抑菌浓度 耐药性
分类号 S852.611 [农业科学—基础兽医学]
  • 相关文献

参考文献6

  • 1王丽平,陆承平,唐家琪.32种抗菌药物对临床分离猪源链球菌的体外抗菌活性[J].微生物学报,2004,44(6):794-799. 被引量：13
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二级参考文献9

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共引文献12

同被引文献22

  • 1许力干,陈泽祥,吴礼洁,潘艳,谢永平,朱贤龙.猪链球菌广西分离株耐药性分析[J].中国畜牧兽医,2006,33(9). 被引量：12
  • 2Wei Zi-gong, Li Ran, Zhang An-ding, et al. Characterization of Streptococcus suis isolates from the diseased pigs in China between 2003 and 2007 [J]. Vet Microbiol, 2009, 137(1-2): 196-201.
  • 3Yu Hong-jie, Jing Huai-qi, Chen Zhi-hai, et al. Human Strepto- coccus suis outbreak, Sichuan, China [J]. Emerg Infect Dis, 2006, 12: 914-920.
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  • 5Drlica K, Malik M, Kems R J, et al. Quinolone-mediated bacte- rial death [J]. Antimicrob Agents Chemother, 2008, 52 (2): 385-392.
  • 6Escudero J A, MiUan A S, Catalan A, et al. First characteriza- tion of fluoroquinolone resistant in Streptococcus suis [J]. An- timicrob Agents Chemother, 2007, 51(2): 777-782.
  • 7Escudero J A, Millan A S, Gutierrez B, et al. Fluoroquinolone efflux in Streptococcus suis is mediated by SatAB and not by SmrA [J]. Antimicrob Agents Chemother, 2011, 55(12): 5850- 5860.
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  • 10Robicsek A, Strahilevitz J, Jacoby G A, et al. Fluoroquinolone- modifying enzyme: a new adaptation of a common aminoglyco- side acetyltransferase [J]. Nat Med, 2006, 12(1): 83-88.

引证文献2

二级引证文献2

中国兽医杂志
2012年 第2期

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