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老年心衰恶病质患者肿瘤坏死因子的变化

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摘要 目的:观察心衰恶病质患者血清肿瘤坏死因子-α(TNF-α)的变化及临床意义。方法:入选60例老年心衰恶病质患者及30例老年心衰患者,采用放射免疫法测定血清TNF-α的浓度,用心脏超声测定左室射血分数(LVEF)。结果:心衰恶病质组的LVEF与对照组比较明显降低(P<0.01),TNF-α明显升高(P<0.01)。结论:心衰恶病质患者TNF-α明显高于普通的心衰患者,其浓度与心衰的严重程度有关。
作者 祁美苹 韩静
出处 《包头医学院学报》 CAS 2012年第1期77-79,共3页 Journal of Baotou Medical College
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