摘要
目的探讨冠心病患者血清C反应蛋白(CRP)水平对冠心病发病的临床意义及对病情预测的价值。方法选取90例冠心病患者和同期体检的知情同意的健康体检人25例分别作为实验组和对照组,其中实验组中稳定型心绞痛(SAP组)30例,不稳定型心绞痛患者(UAP组)30例,急性心肌梗死(AMI组)30例。分别在其入院或体检时抽取空腹静脉血,测定血清CRP含量,观察其CRP的变化。结果实验组中UAP、AMI患者CRP含量高于对照组(P<0.05),SAP、UAP及UAP患者CRP水平依次升高且UAP和AMI两组间有显著性差异(P<0.05)。结论CRP水平与冠心病的病变程度有明显的相关性,早期检测CRP水平对于冠心病的早期评估和控制有重要作用,并可减少心血管病患者急性事件的发生。
Objective To study the correlations between serum level of C-reactive protein and the clinical significance in onset of patients with coronary heart diseases（CHD） and its value in prediction of CHD.Methods Ninety cases of CHD（trial group） and 25 healthy persons（control group） were selected and serum levels of CRP were measured.Results Serum levels of CRP in patients with unstable angina（UA） and patients with acute myocardial infarction（AMI） were much higher than that of normal control group（P0.05）.The degree of increase of serum level of CRP in patients was proportional with different grade of severity of CHD（in order of increase in serum levels： stable angina pectoris,unstable angina pectoris and acute myocardial infarction） and there was significant difference between patients with UA and patients with AMI（P0.05）.Conclusion There was significant correlation between serum level of CRP and degree of severity of CHD.Serum level of CRP plays an important role in early assessment,control of CHD and reducing the incidence of accidents and mortality rate of patients with cardiovascular diseases.
出处
《临床和实验医学杂志》
2012年第6期441-442,共2页
Journal of Clinical and Experimental Medicine
关键词
冠心病
C反应蛋白
相关性
Coronary heart disease
CRP
Correlation
