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活化肝星状细胞的信号传导 被引量:4

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摘要 肝纤维化是肝脏对各种急慢性肝损伤的疤痕修复反应的结果,是各种幔性肝病向肝硬化进展的共同环节,其最主要的特征是以胶原为主的细胞外基质(ECM)的生成与降解失衡,在肝脏中的过度沉积。活化的肝星状细胞(HSC)是肝纤维化发生时ECM的主要来源。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2012年第3期238-240,共3页 Chinese Journal of Hepatology
基金 国家自然科学基金(81070340)
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  • 4Friedman SL. Hepatic stellate cells: protean, multifunctional and enigmatic cells of the liver [J]. Physiol Rev, 2008, 88(1): 125-172.
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  • 7Zuo S,Liu C,Wang J. IGFBP-rP1 induces p21 expression through a p53-independent pathway,leading to cellular senescence of MCF-7 breast cancer cells[J].{H}Journal of Cancer Research and Clinical Oncology,2012,(06):1045-1055.
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