摘要
目的:观察没食子、桑白皮、石榴皮、月季花4种维药体外对白色念珠菌的抑制作用,并对4种药物的抑菌和杀菌效果进行评价。方法:采用常量肉汤稀释法(浓度为1000g/L),检测没食子、桑白皮、石榴皮、月季花4种药物的抑菌和杀菌效果。结果:没食子提取液对白色念珠菌的最低抑菌浓度(MIC)为25g/L,杀菌浓度(MBC)为50g/L;石榴皮浸液对白色念珠菌MIC为125g/L,MBC为250g/L;月季花浸液对白色念珠菌MIC为125g/L,MBC为500g/L,桑白皮浸液对白色念珠菌无抑、杀菌作用。结论:没食子、石榴皮、月季花提取液在体外均具有一定的抗白色念珠菌活性作用,桑白皮浸液在体外对白色念珠菌无抑、杀菌作用。
Objective： To investigate and evaluate the fungistasis and tericidal action of gallnut, cortex mori radi- cis, pomegranate rind and everflowering rose to Candida albicans in vitro. Methods： The fungistasis and tericidal ac- tion of four herbs were detected, and the NCCLS （national committee for clinical laboratory standards）was used to evaluated the concentration. Results： The minimum inhibitory concentration（MIC）of gallnut, pomegranate rind and everflowering rose to the Candida albicans was 25mg/ml, 125mg/ml, 125mg/ml,respectively;The minimal bacteri- cidal concentration（MBC） of gallnut, pomegranate rind and everflowering rose to the Candida albicans was 50rag/ ml, 250mg/ml,500mg/ml respectively. The fungistasis and tericidal action of cortex mori radicis extract to Candida albicans was not observed in vitro. Conclusion： Gallnut, pomegranate rind, and everflowering rose extract all have anti-Candida albicans activity in vitro. The cortex mori radicis extract has no fungistasis and tericidal action ~o Candida albicans in vitro.
出处
《口腔医学研究》
CAS
CSCD
2012年第3期250-251,共2页
Journal of Oral Science Research
基金
新疆自治区青年基金专项基金(编号:2009211B21)
关键词
口腔念珠菌病
没食子
桑白皮
石榴皮
月季花
Oral candidiasis Gallnut Cortex mori radicis Pomegranate rind Everflowering rose
