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肿瘤相关成纤维细胞与肿瘤相关性研究进展 被引量:1

Advances of tumor-associated fibroblasts in carcinogenesis
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摘要 肿瘤微环境中基质细胞对于肿瘤的发生发展具有重要作用。肿瘤相关成纤维细胞(TAF)是数量最丰富的基质细胞,在肿瘤微环境中通过细胞与细胞间相互接触,并在各种可溶性因子的作用下,促进上皮细胞及其他细胞恶性转化。 Stromal cell types of the neoplastic mi nt play important roles in the occurrence and development of tumor. Tumor-associated fibroblasts (TAFs) are the most abundant cells in tumor stroma. They promote the malignant transformation of epithelial cells and other cells through cell-cell communication via various soluble factors.
出处 《国际肿瘤学杂志》 CAS 2012年第3期163-166,共4页 Journal of International Oncology
基金 基金项目:国家自然科学基金资助项目(30972779) 广东省科技计划项目(2009B030801333) 东莞市科技计划项目(8452402301001083)
关键词 血管生成抑制剂 肿瘤相关成纤维细胞 Angiogenesis inhibitors Tumor-associated fibroblast
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  • 1Saffarian S, Collier IE, Marmer BL, Elson EL, Goldberg G. Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen. Science 2004; 306:108-111.
  • 2Boire A, Covic L, Agarwal A, Jacques S, Sheriff S, Kuliopulos A. PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell 2005; 120:303-313.
  • 3Curran S, Murray GI. Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis. Eur J Cancer 2000; 36:1621-1630.
  • 4Nomura H, Fujimoto N, Seiki M, Mai M, Okada Y. Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas. Int J Cancer 1996; 69:9-16.
  • 5Mori M, Mimon K, Sadanaga N, Inoue H, Tanaka Y, Mafune K, Ueo H, Bamard GF. Prognostic impact of tissue inhibitor of matrix metalloproteinase-1 in esophageal carcinoma. Int J Cancer 2000; 88:575-578.
  • 6Gress TM, Muller-Pillasch F, Lerch MM, Friess H, Buchler M, Adler G. Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int J Cancer 1995; 62: 407-413.
  • 7Brew K, Dinakarpandian D, Nagase H. Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim Biophys Acta 2000; 1477:267-283.
  • 8Baker T, Tickle S, Wasan H, Docherty A, Isenberg D, Waxman J. Serum metalloproteinases and their inhibitors: markers for malignant potential. Br J Cancer 1994; 70:506-512.
  • 9Oberg A, Hoyhtya M, Tavelin B, Stenling R, Lindmark G. Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metaUoproteinases (TIMP-1, TIMP-2) in colorectal cancer. Anticancer Res 2000; 20:1085-1091.
  • 10Sobin LH, Wittekand CH, editors. TNM Classification of Malignant Tumors. 6th ed. New York: Wiley-Liss, 2002.

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