摘要
越来越多的研究表明长期高糖状态可引起中枢神经系统损害,进而引起认知功能障碍,发展为糖尿病脑病。糖尿病脑病是一种以认知功能障碍以及学习和记忆能力下降为主要临床表现的慢性进行性疾病,其发病机制及治疗方法目前虽不清楚,但无疑已成为研究的热点。目前用于糖尿病脑病治疗的药物主要有作用于血管的药物、作用于G蛋白耦联受体的药物、抗氧化药物等。
An increasing number of researches indicate that long-term hyperglycemia can damage the central nervous system and cause cognitive dysfunction, then develop into diabetes encephalopathy. Diabetic encephalopathy is characterized by cognitive dysfunction and failure of learning and memory. Although its pathogenic mechanism is not clear,diabetic encephalopathy has already become a hot topic today. The pharmacotherapy of diabetes encephalopathy includes vasoactive drugs, agents acting on G-protein coupled receptors, antioxidant drugs and some other medicines.
出处
《国际内分泌代谢杂志》
北大核心
2012年第2期87-90,共4页
International Journal of Endocrinology and Metabolism
基金
基金项目:国家自然科学基金资助项目(81170752)
重庆市自然科学基金资助项目(2010BB5396)
重庆市卫生局科技重点资助项目(2010-1-8)
重庆医科大学科研基金资助项目(2007018)
关键词
糖尿病脑病
认知障碍
药物治疗
Diabetic encephalopathy
Cognitive dysfunction
Pharmacotherapy