摘要
目的:研究运脾复方儿宝颗粒对小儿厌食症动物模型下丘脑CCK8和βEP的调节作用。方法:模拟小儿厌食症的主要病因制作幼龄大鼠厌食模型,用儿宝颗粒治疗,用放射免疫检测技术测定实验动物下丘脑CCK8和βEP的含量。结果:模型动物下丘脑CCK8浓度显著增高(P<0.05),βEP浓度无明显变化(P>0.05);儿宝颗粒治疗组CCK8含量恢复正常,βEP含量显著增高(P<0.01)。结论:儿宝颗粒能明显抑制该模型下丘脑CCK8分泌,同时促进下丘脑βEP分泌。
Objective:To study the effects of Erbao Granules on CCK 8 AND β EP in hypothalamus of juvenile animal model with anorexia.Method:The model was established by imitating the major cause of children anorexia,and then was treated with Erbao Granules.The CCK 8 and β EP concentration in hypothalamus of animals were examined by radioimmunoassay.Resust:There was an obvious increase of CCK 8 concentration in the model(P<0.05) which can be cured by Erbao Granulas.And no change in β EP of model,but it increased significantly in large dose group(P<0.01).Conclusion:Erbao Granules was effective on decreasing CCK 8 and increasing β EP concentration in hypothalamus of the animal model.
出处
《安徽中医学院学报》
CAS
2000年第1期39-41,共3页
Journal of Anhui Traditional Chinese Medical College
基金
国家自然科学基金!资助课题 (NO .3 9670 896)
