摘要
目的:观察丙泊酚联合咪达唑仑在ICU机械通气镇静治疗中的临床效果。方法:选取ICU机械通气的患者60例,随机分为观察组和对照组。观察组给予丙泊酚联合咪达唑仑治疗,对照组给予咪达唑仑治疗,比较两组患者治疗前后的临床情况。结果:观察组的药物起效时间、停药后的苏醒时间、达到满意的镇静深度时间均明显短于对照组(P<0.05);两组患者治疗前后的生命体征有明显变化(P<0.05)。结论:丙泊酚联合咪达唑仑在ICU机械通气镇静中的效果满意,优于单纯咪达唑仑的镇静效果。
Abstract Objective ：To evaluate the effect of propofol and midazolam for sedation in me- chanically ventilated in ICU treatment clini- cal effect. Methods：the ICU patients receiv- ing mechanical ventilation in 60 cases, were randomly divided into observation group and control group. Observation group received propofol and midazo｜am treatment, the con- trol group was given treatment of midazo- lain, compared two groups of patients before and ＇after treatment in the clinical situation. Results： the observation group drug onset time, recovery time after stopping medicine, to the satisfaction of the depth of sedation, time was shorter than in control group （ P 〈 0, 05 ） ;two patients vital signs changes obvi- ously（ P 〈 0.05 ）. Conclusion ： [＇ropofol and midazolam for sedation in mechanically ven- tilated in ICU satisfied with the results,better than midazolam sedative effect,worthy of reference.
关键词
丙泊酚
咪达唑仑
机械通气
镇静
Propofol
Midazolam sedation
Mechanical ventilation
