期刊文献+

Analysis of Caenorhabditis elegans in microfluidic devices 被引量:3

Analysis of Caenorhabditis elegans in microfluidic devices
原文传递
导出
摘要 Caenorhabditis elegans (C. elegans) is widely adopted as a model organism for a variety of biological studies including development, genetics and neurobiology. Micro-scale microfluidic technology is capable of handling single or populations of C. elegans in high throughput format and allows for the precise spatial and temporal control of their environment, which is well suited for the study of worms in different aspects. In this review, we highlight the recent advances in microfluidic technology for the analysis of worms ranging from behavioral studies to neurobiology. We believe that microfluidic device can further be applied to study the different aspects of worms, extending from fundamental investigation of behavioral dynamics to more complicated biological processes including neurochemistry and learning behaviors. Caenorhabditis elegans (C. elegans) is widely adopted as a model organism for a variety of biological studies including development, genetics and neurobiology. Microscale microfluidic technology is capable of handling single or populations of C. elegans in high throughput format and allows for the precise spatial and temporal control of their environment, which is well suited for the study of worms in different aspects. In this review, we highlight the recent advances in microfluidic technology for the analysis of worms ranging from behavioral studies to neurobiology. We believe that microfluidic device can further be applied to study the different aspects of worms, extending from fundamental investigation of behavioral dynamics to more complicated biological processes including neurochemistry and learning behaviors.
出处 《Science China Chemistry》 SCIE EI CAS 2012年第4期484-493,共10页 中国科学(化学英文版)
基金 supported by the Knowledge Innovation Program of the Chinese Academy of Sciences (KJCX2-YW-H18) Instrument Research and Development Program of the Chinese Academy of Sciences (YZ200908) the National Natural Science Foundation of China (11161160552)
关键词 microfluidic Caenorhabditis elegans behavior neurobiology aging 微流体装置 线虫 神经生物学 模式生物 流体技术 行为研究 生物过程 行为动态
  • 相关文献

参考文献1

二级参考文献14

  • 1Amber L. Graves,Windy A. Boyd,Phillip L. Williams.Using Transgenic Caenorhabditis elegans in Soil Toxicity Testing[J].Archives of Environmental Contamination and Toxicology.2005(4)
  • 2C. L. Peredney,P. L. Williams.Utility of Caenorhabditis elegans for Assessing Heavy Metal Contamination in Artificial Soil[J].Archives of Environmental Contamination and Toxicology.2000(1)
  • 3M. H. A. Z. Mutwakil,J. P. Reader,D. M. Holdich,P. R. Smithurst,E. P. M. Candido,D. Jones,E. G. Stringham,D. I. de Pomerai.Use of Stress-Inducible Transgenic Nematodes as Biomarkers of Heavy Metal Pollution in Water Samples from an English River System[J].Archives of Environmental Contamination and Toxicology.1997(2)
  • 4Steven G. Donkin,David B. Dusenbery.A soil toxicity test using the nematode Caenorhabditis elegans and an effective method of recovery[J].Archives of Environmental Contamination and Toxicology.1993(2)
  • 5Anderson G L,Cole R D,Williams P L.Assessingbehavioral toxicity with Caenorhabditis elegans[].Environmental Toxicology and Chemistry.2004
  • 6Beauvais S L,Jones S B,Parris J T,Brewer S K,Little E E.Cholinergic and behavioral neurotoxicity of carbaryl andcadmium to larva rainbow trout (Oncorhynchus mykiss)[].Ecotoxicology and Environmental Safety.2001
  • 7Boyd W A,Cole R D,Anderson G L,Williams P L.Thee-ects of metals and food availability on the behavior ofCaenorhabditis elegans[].Environmental Toxicology.2003
  • 8Donkin S,Williams P L.In-uence of developmentalstage, salts and food presence on various end points usingCaenorhabditis elegans for aquatic toxicity testing[].Environmental Toxicology and Chemistry.1995
  • 9Graves A L,Boyd W A,Williams P L.Using transgenicCaenorhabditis elegans in soil toxicity testing[].Arch Envi-ron Contam Toxicol.2005
  • 10Riddle D L,Blumenthal T,Meyer B J,Priess J R.C. elegans II. Plainview[]..1997

共引文献21

同被引文献90

引证文献3

二级引证文献29

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部