摘要
目的探讨早期肠内营养支持在重症脑血管病治疗中的临床应用价值。方法选择笔者所在科室2008年1月~2011年6月收治的重症脑血管病患者112例,随机分为治疗组和对照组,各56例。治疗组给予肠内营养制剂,对照组给予肠外营养治疗,分别于营养支持治疗后1d和21d后对两组患者的生化指标,以及21d后免疫学指标和NIHSS评分、并发症发生率等指标进行比较。结果两组患者营养支持治疗后1d在生化指标等各项观察指标差异无统计学意义(P>0.05),治疗21d后治疗组各项生化指标均显著好于对照组(P<0.05);治疗组21d后免疫学指标除IgM和IgG外均显著好于对照组(P<0.05);两组NIHSS评分均有改善,但治疗组改善优于对照组(P<0.05);治疗组并发症发生率显著低于对照组(P<0.05)。结论早期肠内营养干预能够改善急性重症脑血管病患者的营养、免疫状态,降低并发症发生率,有助于改善患者近期的预后,值得临床推广。
Objective To study the clinical value of early enteral nutrition in patients with severe cerebral vascular disease.Methods 112 patients with severe cerebral vascular disease were selected and divided into two groups each for 56,patients in treatment group were given enteral nutrition preparation,others in control group were given parenteral nutrition,biochemical and immunological indexes,scores of NIHSS and complication rate were compared.Results All the indexes after 1day treatment of two groups were no difference(P 0.05),however,the biochemical index after 21 day of treatment group were significantly better than that of control group(P 0.05),and the NIHSS scores and the indexes except IgM and IgG of treatment group were all significantly better than control group(P 0.05).Conclusion Early enteral nutrition can significantly improve the level of nutrition and immune,and decrease the complication rate and deserve to clinical.
出处
《中国医药科学》
2012年第5期29-30,33,共3页
China Medicine And Pharmacy
关键词
重症脑血管病
肠内营养
预后
并发症
Severe cerebral vascular disease
Enteral nutrition
Prognosis
Complication