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缺氧诱导因子-1α在白血病中的表达及其意义

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摘要 缺氧诱导因子(HIF)-1是由两个亚基组成的转录调节因子,在缺氧环境下细胞基因转录调控中起关键作用。多种实体肿瘤、白血病细胞中HIF-1α表达上调、活性增强,现就HIF-1α在白血病中的表达、调节及意义进行综述。
作者 张琪 秘营昌
出处 《国际输血及血液学杂志》 CAS 2012年第2期135-137,共3页 International Journal of Blood Transfusion and Hematology
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