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贝那普利联合比索洛尔对急性心肌梗死晚期左心室重构的影响 被引量:5

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摘要 目的探讨急性心肌梗死(AMI)后应用贝那普利联合比索洛尔治疗对晚期左心室重构的影响。方法将121例AMI患者随机分成治疗组(贝那普利联合比索洛尔)63例和对照组(贝那普利)58例,采用彩色多普勒心动超声仪分别于发病后早期(<24h)、3个月、6个月末连续随访并测量、计算左心室形态、构型等多项指标。结果静脉滴注尿激酶溶栓后,对照组58例患者的血管开通率为46.9%,治疗组63例患者的血管开通率为48.8%,两组的血管开通率没有显著性的差异。治疗组患者,从治疗早期到6个月,患者左心室形态一直处于逐渐扩大状态,而且在6个月末,患者的左心室扩展到了最大。对照组患者左心室的扩大程度,比治疗组患者表现的更明显。通过在同期比较对照组与治疗组患者的左心室变化情况,可知左心室形态,均处于逐渐扩大的状态,差异具有统计学意义。在6个月末的时候,差异最为明显,具有统计学显著差异。在6个月随访期间,121例患者中,发生心力衰竭的共有6例。其中,治疗组3例,占治疗组总人数的4.76%;对照组3例,占对照组总人数的5.17%,两组差异无统计学意义。结论 AMI后应用贝那普利联合比索洛尔对晚期左心室重构的抑制作用明显优于单用贝那普利。
出处 《当代医学》 2012年第9期71-72,共2页 Contemporary Medicine
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参考文献7

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