摘要
背景:地方性氟骨症膝关节损害是一个复杂的慢性全身性疾病,可造成膝关节骨周,骨质的损害。目的:观察人工全膝关节置换治疗地方性氟骨症所致的膝关节损害的临床疗效。方法:纳入2010-03/2011-10依据地方性流行病学、氟斑牙、临床表现及影像学检查确诊由氟骨症所致的膝关节损害患者9例,均行双侧人工全膝关节置换,于置换前及本次随访时根据美国特种外科医院膝关节评分系统进行临床疗效评估。结果与结论:膝关节置换后,美国特种外科医院膝关节评分结果显示优5例,良3例,可1例。患者治疗后在疼痛、功能以及关节活动度等方面均明显改善。说明人工全膝关节置换是治疗地方性氟骨症所致的膝关节损害的有效方法。
BACKGROUND：Knee osteoarthritis caused by endemic skeletal fluorosis is a complex and chronic systemic disease,which can cause the damage of surrounding bone and sclerotin of knee joint.OBJECTIVE：To investigate the effect of total knee arthroplasty （TKA） in the treatment of knee osteoarthritis caused by endemic skeletal fluorosis.METHODS：Nine patients suffered from knee osteoarthritis caused by skeletal fluorosis that diagnosed by local epidemiology,dental fluorosis,clinical and imaging from March 2010 to October 2011 and all the patients were treated with bilateral TKA.The clinical efficacy was evaluated according to the knee scoring system of United States Hospital for Special Surgery before arthroplasty and final follow-up after arthroplasty.RESULTS AND CONCLUSION：Score results showed that 5 knees were excellent,3 knees were good and 1 knee was fair after knee arthroplasty.All patients have been improved in pain,function and range of motion.TKA is an effective method for the treatment of knee osteoarthritis caused by skeletal fluorosis.
出处
《中国组织工程研究》
CAS
CSCD
2012年第9期1555-1558,共4页
Chinese Journal of Tissue Engineering Research
基金
2010年度国际合作计划专项经费项目(2010DFB30530)
课题名称:地方性氟中毒发病机制及防治研究~~
