摘要
目的:观察血必净注射液对急性肺损伤(ALI)病人呼吸功能和早期血清炎性介质释放的影响。方法:60例ALI病人依据"不平衡指数最小的分配原则"随机分为西医常规治疗组(对照组,30例)和西医联合血必净注射液组(研究组,30例),比较两组病人入院时及治疗第7d的动脉血气分析、白细胞介素-6(IL-6)、白细胞介素-10(IL-10)、肿瘤坏死因子-α(TNF-α)和超敏C反应蛋白(HS-CRP)变化,以及急性生理学与慢性健康状况评分系统II(APACHEII)评分、氧合指数(OI)变化和机械通气时间。结果:西医联合血必净注射液组病人血清HS-CRP、TNF-α、IL-6和IL-10水平均明显降低,APALHEII评分和(OI),改善机械通气时间缩短。结论:AIL病人早期西医联合血必净注射液可降低炎性反应,改善动脉血氧合,缩短机械通气时间,从而改善预后。
Objective：To observe the effects of the Xue Bi Jing injection against respiratory function and early inflammatory response in patients with ALI.Methods：60 cases were randomly divided into 2 groups.The control group（30） was given conventional treatment;the observation group（30） was given Xue Bi Jing injection.Results：Serum of the HS-CRP,TNF-alpha,IL-6 and IL-10 water was significantly reduced in the observation group,APALHEII score and（OI）,the mechanical ventilation time was improved.Conclusion：Western plus Xue Bi Jing injection could reduce the inflammatory response,improve arterial oxygenation,and shorten the duration of mechanical ventilation,thereby improving the prognosis.
出处
《中医临床研究》
2012年第5期6-8,共3页
Clinical Journal Of Chinese Medicine
关键词
急性肺损伤
血必净注射液
炎性反应
呼吸功能
Acute lung injury
Xue Bi Jing injection
Inflammatory response
Respiratory function
