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心肌肌钙蛋白检测对判断急性心肌梗死治疗效果的作用 被引量:1

The Effect of Cardiac Troponin Testing on the Therapeutical Judgement of Acute Myocardial Infarction
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摘要 目的:探讨血清心肌肌钙蛋白I(cTnI)对判断急性心肌梗死(AMI)治疗效果的作用。方法:在进行溶栓治疗的同时,测定96例AMI患者血清中的cTnI和与肌酸激酶同工酶(CK-MB),并观察其动态变化。结果:入院72h内,cTnI检测阳性率明显高于CK-MB(P<0.01)。cTnI和CK-MB开始升高时间在溶栓再通者中有显著性差异(P<0.01);在溶栓未通者中无显著性差异(P>0.05)。cTnI与CK-MB高峰出现时间在溶栓未通者中有显著性差异(P<0.01);在溶栓再通者中无显著性差异(P>0.05)。cTn I与CK-MB恢复正常时间在溶栓再通者与溶栓未通者中均有显著性差异(P<0.01)。结论:动态检测cTnI对判断AMI治疗效果较CK-MB更有价值。 Objective: To investigate the effect of serum cardiac troponin I(cTnI)testing on the therapeutical judgement of the acute myocardial infarction c(AMI).Method: During thrombolytic therapy at the same time,serum cTnI and creatine kinase(CK-MB)in 96 cases with AMI were measured,and its dynamics was observed.Result: Admission within 72h,cTnI positive rate was significantly higher than that of CK-MB(P 0.01).The time of cTnI and CK-MB beginning to rise had significant difference(P 0.01) in the hrombolytic recanalization patients;thrombolytic who did not pass without significant difference(P 0.05).The peak times of cTnI and CK-MB had a significant difference(P 0.01)in the thrombolysis who did not pass;who thrombolytic recanalization was no significant difference(P 0.05).cTnI and CK-MB recovery time in the thrombolytic thrombolytic recanalization and those who did not pass were significant differences(P 0.01).Conclusion: Dynamic detection of cTnI for AMI is more valuable than CK-MB in determining the treatment effect.
出处 《河北医学》 CAS 2012年第3期322-324,共3页 Hebei Medicine
关键词 急性心肌梗死 心肌肌钙蛋白I 肌酸激酶同工酶 Acute myocardial infarction Cardiac troponin I CK-MB
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