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硫氧还蛋白还原酶研究进展 被引量:3

Progress of the study on thioredoxin reductase
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摘要 硒蛋白是人和动物必需微量元素硒的主要功能表现形式,硫氧还蛋白还原酶(TrxR)是比较重要的硒蛋白之一,本文对硫氧还蛋白还原酶的分子生物学特点、生物功能、其与某些人类疾病发病机制的关系以及其抑制剂的研究进展进行综述,以期为缺硒性地方病的研究开拓新的思路。 Essential trace element selenium (Se) exerts its biological functions in vivo mainly through selenoproteins. Thioredoxin reductase (TrxR) is one of the important selenoproteins. By reviewing the type, biological characteristics,it's relationship with some disease and suppressor of TrxR, this paper aims to provide new ideas for research of endemic disease of selenium deficiency
出处 《国外医学(医学地理分册)》 CAS 2012年第1期60-63,共4页 Foreign Medical Sciences:Section of Medgeography
基金 国家自然科学基金资助项目(No.30671820 81172610)
关键词 硫氧还蛋白还原酶 结构功能 疾病易感性 抑制剂 TrxR biological characteristics disease susceptibility suppressor
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同被引文献55

  • 1王咏梅.自由基与谷胱甘肽过氧化物酶[J].解放军药学学报,2005,21(5):369-371. 被引量:116
  • 2曹丹阳.硒与心血管疾病[J].广东微量元素科学,2005,12(7):1-4. 被引量:10
  • 3白晓琴,杨建一,李莉.硒对生殖的影响[J].中国优生与遗传杂志,2006,14(9):1-2. 被引量:7
  • 4付作昌,牛莉莉.硒营养微量元素与人体健康[J].赤峰学院学报(自然科学版),2007,23(1):111-112. 被引量:5
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