摘要
目的 研究颅脑损伤后下丘脑、垂体、甲状腺功能改变及意义。 方法 应用磁性酶联免疫定量分析法检测１５６ 例急性颅脑损伤患者血清泌乳素（ＰＲＬ） 、促卵泡生成素（ＦＳＨ）、促甲状腺激素（ＴＳＨ）、甲状腺素（Ｔ３ 和Ｔ４） 水平的变化，并与１００ 例正常对照组比较。 结果 颅脑损伤急性期血清ＰＲＬ、ＦＳＨ、Ｔ４ 含量显著升高，而Ｔ３ 显著降低；分组资料表明，颅脑损伤愈严重，昏迷愈深，上述指标变化愈明显。部分病例受伤７２ ｈ 后及２ 周后复测，上述指标逐渐恢复正常。结论 颅脑损伤急性期内分泌功能有明显异常变化。
Objective To study the function changes of hypothalamus, pituitarium and thyroxine in the patients after craniocerebral trauma. Methods By using magnetic enzyme linked immunosorbent assay, we observed the changes of prolactin(PRL),follicle stimulating hormone(FSH),thyroid stimulating hormone(TSH) and thyroxine(T 3, T 4) in the blood from 156 patients with craniocerebral trauma.Then, these changes were compared with 100 normal control persons. Results In the acute stage of craniocerebral trauma,PRL,FSH and T 4 in the blood were significantly increased, while T 3 was decreased greatly. The grouped material showed that the severer brain injury was and the deeper coma degree emerged, the more obviously these indexes changed.These data were close to normal after 3 days and 14 days respectively in some patients with trauma. Conclusions The endocrine function changed significantly in the acute stage of the craniocerebral trauma.
出处
《中华创伤杂志》
CAS
CSCD
北大核心
2000年第1期32-34,共3页
Chinese Journal of Trauma
关键词
颅脑损伤
血清
垂体前叶激素
甲状腺素
Brain injuries
Pituitary hormones, anterior
Thyroid hormones
Mspeia
