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血气分析、呼气峰流速联合血浆脑利钠肽检测在呼吸困难鉴别诊断中的价值 被引量:1

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摘要 目的探讨血气分析、呼气峰流速(PEF)联合血浆脑利钠肽(BNP)检测鉴别心源性与肺源性呼吸困难的价值。方法选择呼吸困难患者175例,其中肺源性呼吸困难患者97例、心源性呼吸困难患者78例。采用化学发光法测定其血浆BNP水平,并对BNP水平在100~500 pg/mL患者行血气分析和呼气峰流速检测。结果心源性呼吸困难患者血浆BNP水平明显高于肺源性呼吸困难患者(P<0.01)。BNP水平在100~500 pg/mL时,呼吸困难发生率为60.29%,与BNP<100 pg/mL(15.58%)及BNP>500 pg/mL(83.33%)比较均有统计学意义(P均<0.01)。BNP水平在100~500 pg/mL时,心源性、肺源性呼吸困难患者的PaO2、PaCO2、P(A-a)O2和PEF水平比较有统计学意义(P均<0.01)。结论特定BNP水平联合血气分析、呼气峰流速检测能更快速、简便地鉴别肺源性、心源性呼吸困难。
出处 《山东医药》 CAS 2012年第9期81-82,共2页 Shandong Medical Journal
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