摘要
目的:观察复方倍他米松联合苄星青霉素深部肌内注射治疗外耳湿疹的疗效。方法:60例患者随机分为治疗组和对照组2组。治疗组30例,复方倍他米松注射液1ml;苄星青霉素120万U,分两侧臀分别行深部肌内注射。对照组30例,给予地氯雷他定5mg,口服,每日1次;阿莫西林胶囊0.5mg,口服,每日3次,两药连续服用1周。2组患者治疗期间均停用其他内外用药,保持局部清洁、干燥,1周后判断疗效。结果:治疗组痊愈率为60.00%,总有效率为96.67%;对照组痊愈率26.67%,总有效率为73.33%。2组痊愈率比较差异有统计学意义(P<0.01)。2组总有效率比较,差异有统计学意义(P<0.05)。治疗组起效时间2h～3d,平均0.5d;对照组起效时间2d～5d,平均2.5d。结论:采用复方倍他米松联合苄星青霉素治疗外耳湿疹方法简单,见效快,疗效好,复发率低,未见不良反应。
Objective：To observe therapy efficacy of external auditory canal eczema by deeply injecting compound betamethasone and benzathine penicillin into patient＇s muscles.Method：Sixty patients were randomly divided into two groups.In the treatment group 30 patients were deeply injected compound betamethasone injection 1 ml and benzathine penicillin 1 200 000 U into muscles on their hips both sides one times.In the control group 30 patients were given desloratadine 5 mg orally one times a day and amoxicillin capsules 0.5 mg orally three times a day,both kinds of medicine were continuously taken for one week.No other medication was used during the treatment of two groups,keeping skin clean and dry,and judge therapy efficacy after one week.Result：The cure rate was 60.00% and the total efficiency was 96.67% in the treatment group;the cure rate was 26.67% and the total efficiency was 73.33% in the control group.Compare with cure rate of two groups,χ2=6.67,P0.01,in which there was significant difference.Compare with total efficiency of two groups,χ2=4.71,P0.05,in which there was also significant difference.The therapy effect started in two hours quickly and in three days slowly in the treatment group,an average of 0.5 days.The therapy effect started in two days quickly and in five days slowly in the control group,an average of 2.5 days.Conclusion：The method of the treatment group is simple,quick,effective and without adverse reaction.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2012年第7期323-325,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
外耳
湿疹
复方倍他米松
苄星青霉素
肌内注射
external canal
eczema
compound betamethasone
benzathine penicillin
muscle inject
