摘要
目的：观察探讨利维爱与替硝唑泡腾片联合治疗老年性阴道炎的临床疗效，总结其临床价值。方法：选取我院2009年1月至2011年1月108例，随机分为观察组和对照组，各54例，观察组采用利维爱与替硝唑泡腾片联合治疗，对照组单纯采用替硝唑泡腾片治疗，观察对比两组治疗效果，进行统计学分析。结果：治疗一个疗程后，两组的阴道健康状况评分、阴道炎症状评分、阴通脱落细胞成熟指数（MV）、子宫内膜厚度、雌二醇（E2）、促卵泡生成素（VSH）变化比较存在明显差异（P〈0．05），具有统计学意义。观察组在用药后4-6天出现轻度乳房胀痛2例，无需处理持续3～7天后自行缓解，其余患者均无不良反应发生，两组患者不良反应对比无显著差异（P〉0．05），无统计学意义。结论：维爱与替硝唑泡腾片联合治疗老年性阴道炎的临床疗效显著，明显优于单纯采用替硝唑泡腾片治疗，能明显改善临床症状，极少不良反应发生，安全可靠，值得在临床上合理推广应用。
Objective： To observe the study Livial effervescent combination therapy with tinidazole clinical efficacy of senile vaginitis, summarize its clinical value. Methods： 108 patients were randomly divided into two groups and the control group, all 54 patients in the observation group using Livial combination therapy with tinidazole effervescent tablets, effervescent tablets control group were treat- ed using tinidazole, observed and compared two group treatment effects were statistically analyzed. Results： After a course of treatment, two groups of vaginal health score, symptom score vaginitis, vaginal maturation index pass off （MV）, endometrial thickness, estradiol （E2）, follicle stimulating hormone （FSH） changes more significantly different （P 〈0.05）, with statistical significance. Conclusion： D love and tinida- zole effervescent combined treatment of senile vaginitis significant clinical efficacy, safety and reliability, it is reasonable in the clinical application.
