摘要
目的评价我院41例肝移植患者长期生存情况,分析影响肝移植术后长期生存的因素。方法回顾分析2004年6月至2007年1月连续完成的41例肝移植病例,统计生存率,分析死亡原因、并发症情况和再移植原因。结果本组1年、3年、5年实际生存率达到95.00%、87.50%、81.96%。终末期肝病组1、3、5年生存率96.15%、92.31%、88.46%,肝癌组1、3、5年生存率92.86%、78.57%、70.71%。结论肝癌复发、胆道铸型综合征、原发疾病复发、免疫抑制剂副作用是影响本组肝移植术后长期生存的因素。加强围手术期处理是提高肝移植患者术后长期生存率的关键因素。
Objective To evaluate the survival outcomes for 41 cases of liver transplantation and to analysis the factors of impacting long-term postoperative survival outcomes. Methods Clinical data, including survival rate, causes of death ,complications and causes of regraft, for 41 cases of liver transplantation at our institute from June 2004 to January 2007 were retrospectively analyzed, and 41 cases were all followed-up to exceed 5 years. Results The overall patient survival rate was 95.00% ,87.50% and 81.96% in postoperative one year,three year and five year respectively. The patient survival rate in end-stage liver disease group was 96. 15%, 92. 31% and 88.46% in postoperative one year, three year and five year respectively, as well as the patient survival rate in hepatoma group was 92. 86% ,78.57% and 70. 71% in postoperative one year,three year and five year respectively. Conclusions Liver cancer relapse, biliary east syndrome, primarily disease relapse and immunosuppressive agent related disease are the primary causes for influencing long-term survival outcomes. Strengthened treatments in pre-and post-operation are the key factors to improve the patient＇s long-term survival.
出处
《中华临床医师杂志（电子版）》
CAS
2012年第2期65-68,共4页
Chinese Journal of Clinicians(Electronic Edition)
基金
首都特色临床医学应用发展项目(Z0005190043111)
关键词
肝移植
预后
生存率
Liver transplantation
Prognosis
Survival rate
