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盐酸右美托咪定在机械通气患者中的应用 被引量:7

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摘要 目的探讨盐酸右美托咪定应用于机械通气患者的镇静效果和安全性。方法 88例机械通气患者为研究对象,随机分为试验组和对照组。试验组给予盐酸右美托咪定镇静,对照组给予咪达唑仑镇静。结果 2组Ramsay镇静评分均无Ⅴ~Ⅵ级患者,试验组Ⅱ~Ⅳ级患者多于对照组,Ⅰ级患者少于对照组,但差异无统计学意义(P>0.05);试验组镇静起效时间显著和镇静解除时间均显著快于对照组(t=6.394,P<0.05;t=8.591,P<0.05)。2组通气期间平均动脉压,心率和血氧饱和度均无剧烈波动,试验组波动情况小于对照组,但差异无统计学意义(P>0.05)。结论机械通气患者采用盐酸右美托咪定镇静,能达到良好的镇静效果,而且安全性更高,值得临床考虑。
出处 《河北医药》 CAS 2012年第7期989-990,共2页 Hebei Medical Journal
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