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厄贝沙坦联合太极拳运动对早期糖尿病肾病的临床疗效观察 被引量:5

Clinical observation on effect of Irbesartan combined with Taijiquan movement in the treatment of early diabetic nephropathy.
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摘要 目的:观察厄贝沙坦联合太极拳运动对早期糖尿病肾病的临床治疗和康复效果。方法:90例早期DN患者随即分为观察组(厄贝沙坦联合太极拳运动),厄贝沙坦组(厄贝沙坦)及对照组各30例;观察3个月,比较治疗前后患者UAER、β2-MG、血压的变化。结果:治疗后观察组及厄贝沙坦组尿微量白蛋白排泄率(UAER)、尿β2微球蛋白(β2-MG)较治疗前显著下降(P<0.01),且较对照组显著降低(P<0.01),观察组较厄贝沙坦组下降更为显著(P<0.01);三组治疗后收缩压和舒张压较治疗前均有明显下降(P<0.01),观察组较厄贝沙坦组和对照组下降更明显,(P<0.05)。结论:厄贝沙坦联合太极拳运动对早期DN临床和康复疗效确切,可积极稳定的控制血压和显著减少患者尿蛋白排出。 Objective To observe the effect ofcombination of irbesartan and Taijiquan movement onearly stage type 2 diabetic ne- phropathy patients. Methods The 90 early stage type 2 diabetic nephropathy were randomly divided into three groups, observation group ( irbesartan plusTaijiquan movement, n = 30) , ARB group ( irbesartan, n = 30) and control group ( n -- 30) . After 3 months, the patients underwent examinations for changes in the urinary albumin excretion rate (UAER) , urine132microglobulin ( 132 - MG), arterial blood pressure before and after treatment. ResultsObservation group and ARB group decresased the level of UAER, 132 - MG moresignificantly than before ( P 〈 0. 01 ) , and had obviously decreases than control group ( P 〈 0. 01 ), Observation group produced the most obvious reduction compared whith the other group (P 〈 O. O1 ) . The arterial blood pressure of the three groups had significantly decreases , Observation group produced the most obvious reduction (P 〈 O. 05 ) Conclusions The combination of irbesar- tan and Taijiquan movementhave good effects on the treatment and rehablitationof early stage type 2 diabetic nephropathy patients and can obviously reduce urinary albumin excretion.
作者 林恒钊
出处 《中国民族民间医药》 2012年第8期108-109,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词 太极拳运动 厄贝沙坦 糖尿病肾病 尿微量白蛋白 尿Β2微球蛋白 Irbesartan Taijiquan movement Diabetic nephropathy Urinary albumin
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