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1,25二羟基维生素D3与其受体在类风湿关节炎中的作用研究进展 被引量:19

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摘要 维生素D(vitamin D,Vit D)为固醇类衍生物,通过与维生素D受体(vitamin D receptor,VDR)结合,调节骨和钙磷代谢,防治骨质疏松,并影响多种细胞的增殖和分化,调节免疫系统。
作者 洪琼 徐建华
出处 《安徽医学》 2012年第3期371-373,共3页 Anhui Medical Journal
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参考文献28

  • 1Arnson Y,Amital H,Shoefeld Y. Vitamin D and autoimmunity.New etiological and therapentical considerations[J].Annals of the Rheumatic Diseases,2007,(09):l137-1142.
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  • 4Penna G,Adorini L. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation,maturation,activation,and survival of dendritic cells leading to impaired alloreactive T cell activation[J].Journal of Immunology,2000,(05):2405-2411.
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二级参考文献20

  • 1聂国明,余健,邹敏书,罗莉漫,丁冬胜.维生素D_3对幼年类风湿性关节炎患儿的γ干扰素与白细胞介素4反应的研究[J].华南国防医学杂志,2004,18(4):15-17. 被引量:3
  • 2曹丽丽,陈瑞冬,迟兆富.多发性硬化症患者维生素D_3及其受体水平的检测[J].现代免疫学,2005,25(5):383-383. 被引量:7
  • 3唐吉斌,孙芸,陈继忠,张大昌.抗CCP抗体与RF联合检测在类风湿关节炎早期诊断中的意义[J].检验医学与临床,2006,3(1):12-12. 被引量:10
  • 4Cutolo M,Otsa K,Uprus M,et al.Vitamin D in rheumatoid arthritis[J].Autoimmun Rev,2007,7(1):59-64.
  • 5Bukhari M,Harrison B,Lunt M,et al.Time to first occurrence of erosion in inflammatory polyarthritis:results from a prospective community-based study[J].Arthritis Rheum,2001,44(6):1248-1253.
  • 6Eva Zold,Peter Szodoray,Janos Gaal,et al.Vitamin D deficiency in undifferentiated connective tissue disease[J].Arthritis Res Ther,2008,10(5):10-123.
  • 7Hewison M,Freeman L,Hughes SV,et al.Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells[J].Immunology,2003,170(11):5382-5390.
  • 8NEPOM G T.The role of the DR4 shared epitope in selection and commitment of autoreactive T cells in rheumatoid arthritis[J].Rheum Dis Clin North Am,2001,27(2):305-305.
  • 9PANAYI G S,Corrigall V M,Pitzalis C.Pathogenesis of rheumatoid arthritis:the role of T cells and other beasts[J].Rheum Dis Clin of North Am,2001,27(2):317-334.
  • 10YAMANISHI Y,FIRESTEIN G S.Pathogenesis of rheumatiod arthritis:the role of synoviocytes[J].Rheum Dis Clin North Am,2001,27(2):355-371.

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