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慢性鼻炎与西北燥证相关性的病例对照研究 被引量:7

Correlative case-control study on chronic rhinitis and the northwest dryness syndrome
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摘要 目的:探讨新疆吐鲁番、哈密、乌鲁木齐等不同地区慢性鼻炎与西北燥证的罹患关系,分析二者之间病因病机和临床表现方面的相关性。方法:应用临床流行病学病例对照研究方法进行方案设计和对比分析,并依据传统中医理论对西北燥证与慢性鼻炎的关系加以合理解释。结果:慢性鼻炎患者(80例)西北燥证罹患率为47.50%,高于对照组(160例)15.00%(P<0.01);慢性鼻炎患者所罹患西北燥证之临床证候以肺卫孔窍皮肤燥证和肺心脾风火燥证为多见;慢性鼻炎患者中西北燥证罹患者(38例)之病情积分及病情指数均显著高于非罹患者(42例)(P<0.01);聚类分析显示,肺心脾风火燥证与慢性鼻炎证候关联性最强。结论:西北燥证是新疆地区慢性鼻炎的重要危险因素。 Objective: To discuss attack rate correlation between chronic rhinitis and the northwest dryness syndrome in Turpan,Kami,Urumqi in Xinjiang,to analyse correlativity in etiology and pathogenesis and clinical manifestation between them.Methods: Applied clinical epidemiology case-control study method,survey patients with chronic rhinitis,and applied TCM theory to give reasonable explanations about correlativity between the northwest dryness syndrome and chronic rhinitis.Results: The northwest dryness syndrome attack rate was 47.50% among patients of chronic rhinitis,it's higher than control group with attack rate 15.00%(P0.01),the main syndrome and the lung and heart wind-fire pathogen syndrome were frequent in clinical syndrome among the northwest dryness syndrome.There were significant differences(P0.01) on disease condition integral and disease condition index among patients of chronic rhinitis with the northwest dryness syndrome and control group.The lung and heart wind-fire pathogen syndrome correlated with chronic rhinitis most in cluster analysis.Conclusion: the northwest dryness syndrome is an important risk factor for chronic rhinitis,actively carrying out about the northwest dryness syndrome theory and clinical research.
作者 姜德 周铭心
出处 《中华中医药杂志》 CAS CSCD 北大核心 2012年第4期1123-1127,共5页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 国家自然科学基金项目(No.30860349) 自治区自然科学基金项目(No.200821135)~~
关键词 慢性鼻炎 西北燥证 病因病机 相关性 对照研究 Chronic rhinitis Northwest dryness syndrome Etiology and pathogenesis Correlativity Case-control study
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