摘要
微波辐射条件下 ,利用对苯二甲酸和间苯二甲酸与邻苯二胺在多磷酸中的缩合反应 ,合成了 1 ,4 双 ( 2 苯并咪唑基 )苯和 1 ,3 双 ( 2 苯并咪唑基 )苯两种化合物 ,反应时间 1 2min ,产率分别为 77%和 84% ,该条件下的反应速度分别是常规条件下反应速度的 50和 2 0倍 ,且产率与常规反应相当。
Under the microwave irradiation, the 1,4 bis(2 benzimidazolyl)benzene and 1,3 bis(2 benzimidazolyl)benzene were synthesized respectively by condensation of o phenylenediamine and p phthalic acid or m phthalic acid in polyphosphoric acid.The reaction time was 12 min,the yield was 77% and 84% respectively.Compared with the conventional synthesis,the rate of reaction was up to 50 and 20 times faster respectively under microwave irradiation than by conventional method,and the yield was comparable.
出处
《精细化工》
EI
CAS
CSCD
北大核心
2000年第5期256-257,共2页
Fine Chemicals
关键词
苯并咪唑基
微波辐射
苯
合成
有机药物
bis(2 benzimidazolyl)benzene
microwave irradiation
p phthalic acid
m phthalic acid
o phenylenediamine
