摘要
目的:了解南京市妇幼保健院药品不良反应(ADR)发生的特点及一般规律,促进临床合理用药。方法:采用回顾性研究方法,对南京市妇幼保健院2008～2010年收集的138例ADR报告分别从患者性别、年龄、给药途径、药品种类、累及器官或系统、临床表现等方面进行统计、分析。结果:138例ADR中,抗感染药占60.87%,妇科用药占21.01%。静脉给药引发的ADR例数最多,以皮肤及其附件损害最多。结论:临床应合理使用抗感染药物,加强对中药制剂的质量检测和使用规范,以减少或避免ADR的发生。
Objective：To understand the status quo adverse drug reactions（ADR） occurred in our hospital and to promote clinical use of drugs.Methods：By retrospective analysis,138 ADR cases collected from our hospital between 2008 and 2010 were analyzed in respect of gender and age of patient,route of administration,category of drugs,organs and systems involved in ADR and its clinical manifestation.Results：Of total 138 ADR cases,60.87% of cases were induced by anti-infective agents and 21.01% by gynecological medicines.Most of cases were caused by intravenous administration.Main clinical manifestations were lesion of skin and appendixes.Conclusions：Rational use of anti-infective agents should be strengthened.Quality control and standard application of traditional Chinese medicine should be enhanced to reduced or avoid the incidence of ADR.
出处
《儿科药学杂志》
CAS
2012年第4期29-33,共5页
Journal of Pediatric Pharmacy
关键词
药品不良反应
回顾性分析
合理用药
Adverse drug reactions
Retrospective analysis
Rational use of drugs
