摘要
目的通过对暴发性急性胰腺炎(FAP)预后的相关因素的分析,明确与FAP死亡有关的独立危险因素。方法对我院2003年1月至2011年1月间收治的FAP病例共58例按预后将其分为生存组和死亡组,对其临床资料进行回顾性分析,对死亡危险因素进行统计学分析。结果 (1)在年龄、性别、发病时间、就诊时间、病因等无统计学差异(P>0.05)。(2)入院24 h内尿素氮、肌酐、总胆红素、直接胆红素、白细胞计数、红细胞压积指标死亡组明显较生存组高,而白蛋白、血钙相比明显较低,有统计学差异(P<0.0 5)。而血淀粉酶、脂肪酶、钾、钠、血糖无统计学差异。(3)病程中出现单个、三个及以上器官功能障碍数目两组间有明显差异(P<0.05),出现两个器官功能障碍的无统计学差异。(4)两组间手术率无统计学差异。(5)APACHE II、SOFA、Balthazar CT评分两组间无统计学差异。结论起病早期高白细胞计数、高血尿素氮、出现≥3个的多器官功能障碍是FAP死亡的危险因素。
Objective To identify the risk factor from clinical data related to death through the analysis on the related factors of prognoses which influence fulminant acute pancreatitis（FAP）.Methods According to the set standards,58 cases of FAP were collected who received therapy in our hospital from Jan 2003 to Jan 2011.Cases were divided into death group and survival group according to their outcomes.The chinical data were retrospectively analyzed and the death-related tisk factors between two groups were statistically analyzed;Logistic regression analysis method was used in the related factors of death.Results（1） The survival group and death group in age,gender and etiology were no statistic difference（P 0.05）.（2） The BUN,CR,TBIL,DBIL,WBC and HCT of death group were obviously higher than that of survival group within 24 hours after hospitalization,but the ALB,CAwere lower than that of survival group,there was statistic difference（P 0.05）.And AMY、LPS、K、NA、BS had no statistic difference.（3） The numbers of organ dysfunction,single,ternate and above ternate had significant difference in two groups（P 0.05）.Meanwhile,double organ failure had no statistic difference.（4） Operation in two groups had no statistic difference.（5） No statistic difference for the scores of APACHE II,SOFA and Balthazar CT in two groups.Conclusion WBC and BUN appeared in the ternate and more than 3 multiple organs dysfunction are the risk factor of FAP death.
出处
《肝胆胰外科杂志》
CAS
2012年第2期99-102,共4页
Journal of Hepatopancreatobiliary Surgery
