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罂粟碱联合潘生丁对动静脉内瘘早期血栓的防治效果观察 被引量:8

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摘要 目的探讨罂粟碱联合潘生丁对肾功能衰竭、尿毒症患者动静脉内瘘早期血栓防治的临床效果。方法 48例慢性肾功能衰竭、尿毒症需行动静内瘘手术的患者随机分为两组,即罂粟碱与潘生丁联合治疗组(n=25)、阿司匹林对照组(n=23),观察比较两组患者早期血栓形成发生率、内瘘血流量变化情况。结果罂粟碱与潘生丁联合治疗组25例中出现1例早期血栓,占4.0%,阿司匹林对照组23例中出现早期血栓5例,占21.7%,治疗两组比较差异有统计学意义(P<0.01)。结论罂粟碱、潘生丁联合用药通过防止血管痉挛、增加内瘘血流、抗血小板聚集等作用,从而能减少动静脉内瘘早期血栓形成,大大提高动静脉内瘘手术的成功率。
出处 《海南医学》 CAS 2012年第7期66-67,共2页 Hainan Medical Journal
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