期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

多不饱和脂肪酸与IgA肾病的研究进展

原文传递
导出
摘要 自1984年日本学者报道了鱼油能降低IgA肾病（IgA nephropathy,IgAN）患者蛋白尿这一结果[1]以来,激起了世界各地学者的研究热情。研究表明ω-3多不饱和脂肪酸（ω-3 polyunsaturated fatty acidsω-3PUFAs）能抑制导致肾脏疾病的炎症反应。但尚未取得一致的结论,
作者 徐冷楠 吴华
机构地区 卫生部北京医院肾内科
出处 《北京医学》 CAS 2012年第4期316-319,共4页 Beijing Medical Journal
关键词 Ω-3多不饱和脂肪酸 IGA肾病 炎症反应 肾脏疾病 蛋白尿 学者
分类号 R692 [医药卫生—泌尿科学]
  • 相关文献

参考文献29

  • 1Hamazaki T,Tateno S,Sbisbido H. Eicosapentaneoic acid and IgA nephropathy[J].Lancet,1984,(8384):1017-1018.
  • 2Fassett RG,Gobe G C,Peake JM. Omega-3 polyunsaturated fatty acids in the treatment of kidney disease[J].American Journal of Kidney Diseases,2010.728-742.
  • 3王海燕.肾脏病学[M]北京:人民卫生出版社,2008993-1016.
  • 4Dong W,Pestka JJ. Persistent dysregulation of IgA production and IgA nephropathy in the B6C3F1 mouse following withdrawal of dietary vomitoxin (deoxynivalenol)[J].Fundamental and Applied Toxicology,1993.38-47.
  • 5Pestka J J,Zhou HR. Interleukin-6-deficient mice refractory to IgA dysregulation but not anorexia induction by vomitoxin (Deoxynivalenol) ingestion[J].Food and Chemical Toxicology,2000,(7):565-575.doi:10.1016/S0278-6915(00)00041-7.
  • 6Jia Q,Shi Y,Bennink MB. Docosahexaenoic acid and eicosapentaenoic acid,but not alpha-linolenic acid,suppress deoxynivalenol-induced experimental IgA nephropathy in mice[J].Journal of Nutrition,2004.1353-1361.
  • 7Jia QS,Zhou HR,Bennink M. Docosahexaenoic acid attenuates mycotoxin-induced immunoglobulin a nephropathy,interleukin-6 transcription,and mitogen-activated protein kinase phosphorylation in mice[J].Journal of Nutrition,2004.3343-3349.
  • 8Jia Q,Zhou HR,Shi Y. Docosahexaenoic acid consumption inhibits deoxynivalenol-induced CREB/ATF1 activation and IL-6 gene transcription in mouse macrophages[J].Journal of Nutrition,2006.366-372.
  • 9Shi Y,Pestka JJ. Mechanisms for suppression of interleukin-6 expression in peritoneal macrophages from docosahexaenoic acid-fed mice[J].Journal of Nutritional Biochemistry,2009.358-368.
  • 10Brown SA,Brown CA,Crowell WA. Effects of dietary polyunsaturated fatty acid supplementation in early renal insufficiency in dogs[J].Journal of Laboratory and Clinical Medicine,2000.275-286.

二级参考文献16

  • 1Reich NH,Troyanov S,Scholey JW,et al.Remission of proteinuria improves prognosis in IgA nephropathy.J Am Soc Nephrol,2007,18:3177-3183.
  • 2Hamazaki T,Tateno S,Sbisbido H.Eicosapentaneoic acid and IgA nephropathy.Lancet,1984,1(8384):1017-1018.
  • 3Cheng IK,Chan PC,Chan MK.The effect of fish-oil dietary supplement on the progression of mesangial IgA glomerulonephritis.Nephrol Dial Transplant,1990,5:241-246.
  • 4Parinyasiri U,Ong-Ajyooth L,Parichatikanond P,et al.Effect of fish oil on oxidative stress,lipid profile and renal function in IgA nephropathy.J Med Assoc Thai,2000,87:143-149.
  • 5Hogg PJ,Lee J,Nardelli N,et al.Clinical Trial to Evaluate Omega-3 Fatty Acids and Alternate Day Prednisone in Patients with IgA Nephropathy:Report from the Southwest Pediatric Nephrology Study Group.J Am Soc Nephrol,2006,1:467-474.
  • 6Bennett WM,Walker RG,Kincaid-Smith P.Treatment of IgA nephropathy with eicosapentanoic acid (EPA):a twoyear prospective trial.Clin Nephrol,1989,31:128-131.
  • 7Pettersson EE,Rekola S,Berglund L,et al.Treatment of IgA nephropathy with omega-3-polyunsaturated fatty acids:a prospective,double-blind,randomized study.Clin Nephrol,1994,41:183-190.
  • 8Donadio JV Jr,Grande JP,Bergstralh EJ,et al.The longterm outcome of patients with IgA nephropathy treated with fish oil in a controlled trial.J Am Soc Nephrol,1999,10:1772-1777.
  • 9Branten AJ,Klasen IS,Wetzels JF.Short-term effects of fish oil treatment on urinary excretion of high-and lowmolecular weight proteins in patients with IgA nephropathy.Clin Nephrol,2002,58:267-274.
  • 10Alexopoulos E,Stangou M,Pantzaki A,et al.Treatment of severe IgA nephropathy with omega-3 fatty acids:the effect of a "very low dose" regimen.Ren Fail,2004,26:453-459.

共引文献6

北京医学
2012年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部