摘要
为临床观察PPH结合芩柏颗粒剂熏洗及九华膏纱条纳肛治疗混合痔的安全性，采用随机方法将180例符合混合痔诊断标准的病例分为PPH加中药组（PPH加芩柏颗粒剂熏洗及九华膏纱条纳肛）、PPH组和外剥内扎术加中药组（外剥内扎术加芩柏颗粒剂熏洗及九华膏纱条纳肛）。观察术后肛门失禁的发生情况，结合直肠肛管测压对肛门功能进行评价。结果显示，3组肛门失禁情况存在显著性差异（P〈0．05）。肛管静息压3组术后均较术前明显降低（P〈0．01），术后PPH加中药组、PPH组肛管静息压明显高于外剥内扎术加中药组（P〈0．05）。肛管最大缩榨压术后PPH加中药组、PPH组明显高于外剥内扎术加中药组（P〈0．05）。肛管舒张压3组术前与术后比较以及术后3组间比较差异均无统计学意义（P〉0．05）。直肠感觉阈值和直肠最大容量PPH加中药组、PPH组术前与术后比较差异无统计学意义（P〉0．05），但外剥内扎术加中药组直肠感觉阈值术后较术前明显降低（P〈0．05），直肠最大容量术后较术前明显升高（P〈0．05）。结果表明，PPH结合芩柏颗粒剂熏洗及九华膏纱条纳肛治疗混合痔，可有效地保护肛垫组织，能最大限度地保护肛门直肠生理功能，具有更好的安全性。
One hundred and eighty patients with mixed hemorrhoids （MH） were divided randomly into three groups. Patients in the 1st group underwent PPH plus traditional Chinese drugs（Qinbai granules fumigation and washing and Jiuhua ointment） put into anus,patients in the 2nd group underwent PPH,and patients in the 3rd group underwent the operation of external dissection ＆ internal ligation plus the same traditional Chinese drugs as in the 1st group. Which Observe the state of anal incontinence in postoperation, and assess anal function by determining anorectal pressure. As results,marked difference existed in anal in- continence among the three groups（ P 〈0.05） ,marked reduction of anal rest pressure existed （postoperatively vs preoperatively） in the 3 groups（ P 〈0.01） ,anal rest pressure more higher was observed in the 1st and 2nd groups than in the 3rd group （ P 〈0.05） ;more higher of postoperative maximum anal contraction pressure was observed in the 1st and 2nd groups than in the 3rd group （ P 〈0.05）. Compared postoperation ＆ preoperation in three groups anal diastolic pressure and among three groups in postoperation had no statistical difference（ P〈0.05）. Compared postoperation ＆ preoperation in 1st group and 2nd group rectal sensation threshold and rectal maximum volume had no statistical difference（ P 〉0. 05） ,while postoperation vs preoperation rectal sensation threshold in 3rd group marked reduction（ P 〈0.05）, but post operation vs preoperation rectal maximum volume marked higher. It is revealed that the combined therapy of PPH plus traditional Chinese drugs can protect anal cushion and anorectal function and better safety.
出处
《中国肛肠病杂志》
2012年第3期9-11,共3页
Chinese Journal of Coloproctology
基金
湖南省教育厅资助项目（10W020）
