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921株结核分枝杆菌耐药性分析

Analysis on Drug Resistance of 921 Mycobacterium Tuberculosis Strains
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摘要 目的:调查结核分枝杆菌的耐药情况,为临床合理用药提供依据。方法:对921例肺结核患者进行结核分枝杆菌培养和药敏试验。结果:单耐药的耐药率由高到低依次是链霉素(18.3%)、异烟肼(14.6%)、利福平(13.1%)、乙胺丁醇(5.3%),耐多药的耐药率为3.3%。19~39岁年龄段无论是单耐药率还是耐多药率都较高,而<18岁年龄段的耐药率最低。结论:结核分枝杆菌的耐药形势比较严峻。 Objective: To explore the drug resistance condition of Mycobacterium tuberculosis and find basis for clinical treatment.Methods: Mycobacterium tuberculosis was isolated from the sputum of 921 patients with pulmonary TB and then the susceptibility test was done.Results: The resistance rates to SM,INH,RFP and EMB were 18.3%,14.6%, 13.1% and 5.3% respectively.Multi-drug resistant rate was 3.3%.in all age groups the resistant rate of 19 ~ 39 group was the highest,while that of 18 group was the lowest.Conclusion: The drug resistance condition of Mycobacterium tuberculosis is serious.
作者 罗燕 谢巧娥
出处 《赣南医学院学报》 2012年第1期76-77,共2页 JOURNAL OF GANNAN MEDICAL UNIVERSITY
关键词 结核分枝杆菌 耐药性 Mycobacterium tuberculosis drug resistance
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