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不同检测方法检测免疫球蛋白轻链比值的比较 被引量:1

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摘要 目的比较流式细胞术法和散射比浊法的轻链κ/λ比值结果是否具有一致性。方法用流式细胞术法和散射比浊法分别对32例患者的外周血B淋巴细胞膜上κ、λ轻链的表达率、血清和尿液中的游离κ、λ轻链含量进行测定,并分别计算κ/λ比值。结果 3个不同组别的标本两两分组,分别进行检测方法的一致性比较,用Kappa检验进行统计分析,结果为B细胞组和血清组的κ值为0.881,血清组和尿液组的κ值为0.885,B细胞组和尿液组的κ值为0.885。结论两种检测方法结果的κ/λ比值有极高的一致性。对于血清和尿液中κ/λ比值异常的标本,建议同时检测B淋巴细胞膜上的κ/λ比值,以确定该标本是否有B淋巴细胞克隆性表达的存在。
出处 《国际检验医学杂志》 CAS 2012年第8期971-971,981,共2页 International Journal of Laboratory Medicine
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