摘要
老年性痴呆,又称阿尔茨海默病(Alzheimer's disease,AD),是发生在老年期及老年前期的一种慢性进行性发展的致死性中枢神经系统神经退行性疾病。随着寿命的延长,AD的患病年龄越来越年轻化,发病率及病死率越来越高。本文结合国内外较新的研究成果,提出了Wnt/β-catenin修饰神经干细胞移植治疗AD的新理念和策略,最终目标是为了改善老年人的身心健康。
Senile dementia, also known as Alzheimer＇s disease （Alzheimer＇s disease, AD）, is a common chronic and progressive degenerative disease of the central nervous system, being a main cause for dementia in presenium and seneetitude. Trend of incidence age of patients with AD gradually gets younger,and its morbidity and mortality also appear a increasing tendency. According to the studies both at home and abroad, we put forward a new ideas about treatment strategies, Wnt/β-eatenin gene modified neural stem cell transplantation, for treatment of Alzheimer＇s Disease, which may improve physical and mental health of the elderly age.
出处
《四川解剖学杂志》
2011年第4期42-45,共4页
Sichuan Journal of Anatomy
基金
2009年度贵州省社会发展科技攻关计划项目
β-catenin基因修饰神经干细胞对痴呆模型大鼠的防治效应(黔科合SY字[2009]3067)
