摘要
目的 :研究肺癌患者体液免疫指标的变化及其与 CEA的关系。方法 :用自动生化分析仪和放免法定量测定 80例肺癌患者的血清球蛋白、Ig G、Ig A、Ig M及补体 3(C3)、补体 (C4)的量 ,设肺部良性疾病肺炎和正常人两组为对照组 ,运用 SPSS软件进行统计。结果 :肺癌组的球蛋白、Ig G、Ig A比肺炎和正常人明显升高 (P<0 .0 5 ) ,C3则比正常人降低 (P<0 .0 5 ) ,Ig M、C4两组差异无显著性 (P>0 .0 5 ) ,CEA阳性和 CEA阴性肺癌患者免疫球蛋白、补体差异均无显著性 (P>0 .0 5 ) ,肺癌患者的血清 CEA与 Ig A呈显著正相关 (P<0 .0 1)。结论 :肺癌患者的体液免疫功能增强。
Objective:To study the changes of globulin,IgG,IgA,IgM,C 3 and C 4 in patients with lung cancer,and find out the correlation between these indexes and CEA.Methods:The serum globulin,IgG,IgA,IgM,C 3 and C 4 were determined by an auto biochemical analyzer,and CEA was determined by radio immunity method in 80 patients,while patients with pneumonia and healthy people were as controls.The method of statistical analysis was SPSS.Results:The sreum globulin,IgG and IgA in patients with lung cancer were significantly higher than those in the two controls (P<0.05),while C 3 was significantly lower than the healthy control (P<0.05).No significant differences of these serum indexes were observed between those with CEA positive and negative in patients with lung cancer.A statistically significant positive correlation was found between CEA and IgA(P<0.01).Conclusion:Humoral immunity of patients with lung cancer was increased.
出处
《肿瘤研究与临床》
CAS
2000年第2期78-80,共3页
Cancer Research and Clinic
